Nasal Administration of Glucagon

<< ENDOCRINE


Considerations:

Low blood sugar in children with diabetes can have varied symptoms. These can include but are not limited to:

  • nervousness,
  • shakiness,
  • weakness,
  • extreme hunger,
  • slight nausea,
  • dizziness,
  • headache,
  • blurred vision,
  • fast heartbeat and/or
  • feeling tired.
  • Based on the student’s Diabetes Medical Management Plan/health care provider’s order, low blood sugar is treated with some type of quick-acting oral sugar, such as candy, icing/cake frosting tube, and/or juice.
  • Severe low blood sugar symptoms include disorientation, unconsciousness, and seizures. If not treated promptly it could lead to death.
  • Glucagon is a medication used in emergency situations when the student is unresponsive or unable to swallow because of very low blood sugar.
  • Given that when a student is having symptoms of severe low blood sugar, it can be a stressful situation, it is highly recommended that you familiarize yourself with the student’s emergency plan beforehand.
  • The school nurse or other qualified health care professional must review the glucagon procedure with staff to ensure that they have the skills to perform this emergency medication administration.
  • Store the Diabetes Medical Management Plan/health care provider’s order and glucagon in a location that is easily accessible during a severe blood sugar event.
  • Be sure that staff members who have regular contact with the student know where the medication is stored.
    • If the student self-carries their glucagon be sure to communicate with the student to know where they store their medication.
  • The school nurse should develop a plan to systematically check the expiration date on medication to ensure medication is not expired.
  • Remember to keep the student’s health care information confidential.

Important storage information:

  • Do not remove the shrink wrap or open the tube until you are ready to give the medication
    • If the tube has been opened, BAQSIMI could be exposed to moisture
    • This could cause the medication to not work as expected

Supplies: 

  • Baqsimi
  • Gloves
  • Healthcare provider’s order
  • Diabetes Medical Management Plan
  • Student’s Individualized Healthcare Plan (IHCP)
  • Parent/guardian authorization form
  • Bulb syringe, if available

Procedure:

  1. Identify that symptoms of a severe low blood sugar reaction are present and that based on the child’s diabetes emergency plan, medication needs to be given
  2. Call for assistance
  3. Ask that another school staff person call 911 or emergency medical services
  4. If able, move the student to a lying position
  5. Explain the procedure to the child at his/her level of understanding
  6. Check the six rights of medication administration and the order to be sure it is:
    1. For the right student
    2. The right medication
    3. The right dose
    4. Being given at the right time
    5. Being given by the right route
    6. Being given for the right reason
  7. Be sure to check the medication to ensure that it has not expired
  8. Review student’s allergy status
  9. Ensure proper documentation of parent/guardian authorization to administer the medication
  10. Wash your hands, if possible
  11. Review the six rights once again to ensure that it is:
    1. For the right student
    2. The right medication
    3. The right dose
    4. Being given at the right time
    5. Being given by the right route
    6. Being given for the right reason
  12. Put on gloves, if gloves are not available, continue with the procedure
  13. Look into the child’s nostrils to determine if there is fluid or mucus in the nostrils.
  14. If drainage or mucus is present, use a bulb syringe to remove it
    • If bulb syringe is not available, medication can still be administered if drainage or mucus is present
  15. Remove the Shrink Wrap by pulling on the red stripe
  16. Open the lid and remove the device from the tube
    1. Caution—do not push the plunger until ready to give the dose
  17. Use your free hand to hold the crown of the head stable
  18. Hold the device between your fingers and thumb
  19. Do not push the plunger yet
  20. Insert tip gently into one nostril until your finger(s) touch the outside of the nose
  21. Push plunger firmly all the way in
    1. Dose is complete when the green line disappears
  22. Remove the device
  23. If the student is not lying on their side, move the student to a side-lying position because vomiting often follows the injection of glucagon
  24. If needed, ask another person for assistance
  25. If alone with student, and you have not already called 911 or emergency medical service, do so now
  26. Monitor the student’s arousal, pulse and respirations and for potential seizure
  27. If student begins to seize, clear the area of anything hard or sharp, to prevent injury
  28. If breathing stops, move the student onto their back
  29. Begin rescue breaths
  30. If breathing and heartbeat stop, begin CPR
  31. As soon as the individual is awake and able to swallow, give the individual a fast-acting source of sugar (such as fruit juice)
  32. Once rescue squad arrives, inform them of medication administered, including type of medication, dose and time
  33. Send along BASQIMI along with used dose
  34. Dispose of all used materials in proper receptacles
  35. Remove gloves and wash hands
  36. Follow up with the parent or guardian and healthcare provider, as needed
  37. Document medication administration in the student’s medication administration log

References:

American Diabetes Association. (n.d.). Hypoglycemia (low blood sugar). Retrieved June 2, 2023, from https://diabetes.org/healthy-living/medication-treatments/blood-glucose-testing-and-control/hypoglycemia

American Diabetes Association. (n.d.). Medications and treatments. Glucagon and other emergency glucose products. Retrieved June 2, 2023, from https://diabetes.org/healthy-living/medication-treatments/glucagon-other-emergency-glucose-products#:~:text=Glucagon%E2%80%94a%20hormone%20that%20raises,you%20in%20case%20of%20emergencies

Centers for Disease Control and Prevention. (2022, January 2). Seizure first aid. Retrieved June 6, 2023, from https://www.cdc.gov/epilepsy/about/first-aid.htm

Eli Lilly and Company. (2020). Baqsimi-glucagon powder. Retrieved June 5, 2023, from https://uspl.lilly.com/baqsimi/baqsimi.html#ug

Eli Lilly and Company. (2020). How to use BAQSIMI . Retrieved April 15, 2020, from  https://www.baqsimi.com/how-to-use-baqsimi.

Levitsky, L.L., & Misra, M. (2022). Hypoglycemia in children and adolescents with type 1 diabetes mellitus. In a J. I. Wolfsdorf (Ed.), UpToDate. Retrieved: June 2, 2023, from https://www.uptodate.com/contents/hypoglycemia-in-children-and-adolescents-with-type-1-diabetes-mellitus

National Association of School Nurses. (2022, June 15). School nursing evidence-based clinical practice guideline: Students with type 1 diabetes toolkit. Retrieved June 2, 2023, from https://cdn.fs.pathlms.com/HRuI7pAvQWiJPZdzH6i8

National Association of School Nurses. (2021). School nursing evidence-based clinical practice guideline: Students with type 1 diabetes. Silver Spring, MD: Author. Retrieved June 2, 2023, from https://learn.nasn.org/courses/37660

National Diabetes Education Program. (2016). Helping the student with diabetes succeed: a guide for school personnel. Retrieved June 2, 2023 from https://diabetes.org/sites/default/files/2020-02/NDEP-School-Guide-Full-508.pdf

Wyckoff, L. (2019). Students with diabetes. In Selekman, J. (Ed.), School nursing, a comprehensive text (3rd ed.). (pp. 575-602). Philadelphia PA.: F.A. Davis Co.


Page last reviewed: February 19, 2025

Page last updated: February 19, 2025


The information and materials presented in this Website are intended for informational purposes only and are not designed to diagnose or treat a health problem or disease, or assist in diagnosis or treatment of the same.  The information is not intended to substitute for, supplement or replace clinical judgment.  If there are any concerns or questions about or relating to a nursing or medical procedure, contact the individual’s healthcare provider.  The information provided on this Website is not intended to be a substitute for medical orders and persons without the proper education, training, supervision and/or licensure should not perform the procedures.